主 讲 人：李君 

　　报告时间：2018年9月7日（周五）上午10:00 

　　报告地点：科研楼502会议室 

　　主讲人介绍： 

　　李君，2017年于中国科学院遗传与发育生物学研究所高彩霞课题组获博士学位，2017年至今在首都师范大学生命科学学院马力耕课题组从事博士后研究。主要研究领域包括植物基因组编辑和拟南芥配子体发育的调控。首次将CRISPR/Cas9技术应用于植物中进行植物基因组编辑；在水稻中建立了一种高效的基因定点替换及插入的基因组编辑体系。 

　　代表性研究论文： 

　　1.         Li J¹, Meng X¹, Zong Y, Chen K, Zhang H, Liu J, Li J*, Gao C* (2016) Gene replacements and insertions in rice by intron targeting using CRISPR/Cas9. Nature Plants, 2 (10), 16139. (¹ co-first authors) (Recommended in F1000Prime). 

　　2.         Shan Q¹, Wang Y¹, Li J¹, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Qiu J*, Gao C* (2013) Targeted genome modification of crop plants using a CRISPR-Cas system. Nature Biotechnology,31, 686-688. (¹ co-first authors). 

　　3.        Li J¹, Zhang H¹, Si X, Tian Y, Chen K, Liu J, Chen H, Gao C* (2017) Generation of thermosensitive male-sterile maize by targeted knockout of the ZmTMS5 gene.Journal of Genetics and Genomics, 44 (9), 465-468. (¹ co-first authors). 

　　4.         李君,张毅,陈坤玲,单奇伟,王延鹏,梁振,高彩霞* (2013) CRISPR/Cas系统：RNA靶向的基因组定向编辑新技术. 遗传. 35(11), 1-9. 

　　5.         Shan Q, Wang Y, Li J, Gao C*(2014) Genome editing in rice and wheat using the CRISPR/Cas system. Nature Protocols, 9, 2395-2410. 

　　6.         Wang C¹, Liu W¹, Wang G¹, Li J, Dong L, Han L, Wang Q, Tian J, Yu Y, Gao C, Kong Z* (2017) KTN80 confers precision to microtubule severing by specific targeting of katanin complexes in plant cells, The EMBO Journal, e201796823. (¹ co-first authors). 

　　7.         Guo L¹, CaoX¹, LiuY¹, LiJ, LiY, LiD, ZhangK, GaoC, DongA, LiuX*(2018)Achromatin loop represses WUSCHELexpression in Arabidopsis,Plant Journal, 94, 1083.(¹ co-first authors). 

　　8.         Shan Q¹, Wang Y¹, Chen K¹, Liang Z, Li J, Zhang Y, Zhang K, Liu J, Voytas D F, Zheng X, Zhang Y*, Gao C* (2013) Rapid and efficient gene modification in rice and Brachypodium using TALENs. Molecular Plant, 6, 1365-1368. (¹ co-first authors). 

　　9.         Zhang Y, Li J, Gao C (2016). Generation of stable transgenic rice (Oryza sativa L.) by Agrobacterium-mediated transformation. Current Protocol Plant Biology, 1, 235–246. 

　　邀请撰写的书的章节: 

　　1.         Jun Li, Xiangbing Meng, Jiayang Li*, Caixia Gao*(2018) Gene replacement by intron targeting with CRISPR-Cas9. Methods in Molecular Biology. 

　　2.         Yi Zhang, Jun Li, Caixia Gao* (2016) Generation of Stable Transgenic Rice (Oryza sativa L.) by Agrobacterium-Mediated Transformation. Current Protocols in Plant Biology, 1, 235-246. 

　　植物遗传与育种研究室 

　　2018.09.04