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  • 姓名: 王磊
  • 性别: 男
  • 职称: 研究员
  • 职务: 无
  • 学历: 博士
  • 电话: 
  • 传真: 0311-85815093
  • 电子邮件: wanglei@sjziam.ac.cn
  • 通讯地址: 河北省石家庄市槐中路286号
    简  历:
  • 1、学习经历

    2004.09-2008.07河北科技师范学院,生命科学系 生物科学专业 学士

    2008.09-2011.07河北师范大学,生命科学院 细胞生物学专业 硕士

    2011.09-2016.11中国科学院遗传与发育生物学研究所,遗传学专业 博士

    2、工作经历

    2016.12-2020.08中国农业科学院深圳农业基因组研究所 博士后研究

    社会任职:
    研究方向:
  • 植物激素信号转导与小麦抗旱机制

    研究内容

    (1)独脚金内酯与植物信号分子karrikins是当前植物学领域的研究热点,它们在调控植物生长发育、植物与丛枝菌根真菌共生以及植物寄生中都具有关键作用。然而,独脚金内酯与karrikins调控这些生物学过程的机制仍有待于研究。课题组将以拟南芥和小麦为研究对象,结合遗传学、生物化学、分子生物学、多组学分析等手段,解析独脚金内酯与karrikins调控植物生长发育、共生和寄生的机制。

    (2)小麦是我国第三大粮食作物,关系国家粮食安全。华北是我国小麦主产区,但长期以来水资源严重匮乏,干旱是制约该地区小麦生产的主要因素之一。然而,目前关于干旱如何影响小麦产量的机制还不清楚,课题组将采取新的策略深入挖掘和鉴定调控小麦干旱条件下高产、稳产的关键基因,进而培育优质抗旱小麦新品种,确保国家粮食安全。

    承担科研项目情况:
    代表论著:

  • 1.Chang, W.#, Qiao, Q.#, Li, Q., Li, X., Li, Y., Huang, X., Wang, Y., Li, J., Wang, B.*, and Wang, L*. Non-transcriptional regulatory activity of SMAX1 and SMXL2 mediates karrikin-regulated seedling response to red light in Arabidopsis. Mol. Plant,2024, 17: 1054-1072.

    2. Li, Q.#, Yu, H.#, Chang, W.#, Chang, S., Guzman, M., Faure, L., Wallner, E.S., Yan, H., Greb, T., Wang, L.,Yao, R.*,Nelson, D. C.* SMXL5 attenuates strigolactone signaling in Arabidopsis thaliana by inhibiting SMXL7 degradation. Mol. Plant, 202417: 631-647.

    3. Liu, Y.#, Liu, P.#, Gao, L.#, Li, Y., Ren, X., Jia, J., Wang, L., Zheng, X., Tong, Y., Pei, H.*, Lu, Z*. Epigenomic identification of vernalization cis-regulatory elements in winter wheat. Genome Biol.,2024,25: 200.

    4. Guo, Y.#, Tan, Y.#, Qu, M.#, Hong, K., Zeng, L., Wang, L., Zhuang, C., Qian, Q., Hu, J.*, and Xiong, G*. OsWR2 recruits HDA704 to regulate the deacetylation of H4K8ac in the promoter of OsABI5 in response to drought stress. J. Integr. Plant Biol.,2023,65: 1651-1669.

    5. Wang, D.#, Li, Y.#, Wang, H.#, Xu, Y.#, Yang, Y.#, Zhou, Y., Chen, Z., Zhou, Y., Gui, L., Guo, Y., Zhou, C., Tang, W., Zheng, S., Wang,L., Guo, X., Zhang, Y., Cui, F., Lin, X., Jiao, Y., He, Y., Li, J.*, He, F.*, Liu, X.*, Xiao, J*. Boosting wheat functional genomics via an indexed EMS mutant library of KN9204. Plant Commun., 2023,4: 100593.

    6. Zhang, H.#, Jin, Z., Cui, F., Zhao, L., Zhang, X., Chen, J., Zhang, J., Li, Y., Li, Y., Niu, Y., Zhang, W., Gao, C., Fu, X., Tong, Y., Wang, L., Ling, H.*, Li, J.*, Xiao, J*.. Epigenetic modifications regulate cultivar-specific root development and metabolic adaptation to nitrogen availability in wheat. Nat. Commun.,2023, 14: 8238.

    7. Zheng J.#, Hong K.#, Zeng L.#, Wang L., Kang S., Qu M., Dai J., Zou L., Zhu L., Tang Z., Meng X., Wang B., Hu J., Zeng D., Zhao Y., Cui P., Wang Q., Qian Q., Wang Y., Li J., and Xiong G*.Karrikin signaling acts parallel to and additively with strigolactone signaling to regulate rice mesocotyl elongation in darkness.Plant Cell, 2020, 32: 2780-2805.

    8. Wang, L.#, Wang, B.#*, Yu, H., Guo, H., Lin, T., Kou, L., Wang, A., Shao, N., Ma, H., Xiong, G., Li, X., Yang, J., Chu, J., Li, J*.Transcriptional regulation of strigolactone signaling in Arabidopsis,Nature,2020,583: 277-281.

    9.Wang, L.#, Xu, Q.#, Yu, H., Ma, H., Li, X., Yang, J., Chu, J., Xie, Q., Wang, Y., Smith, SM.,Li, J., Xiong, G.*, and Wang, B*. Strigolactone and karrikin signaling pathways elicit ubiquitination and proteolysis of SMXL2 to regulate hypocotyl elongation in Arabidopsis,Plant Cell,2020, 32: 2251-2270.

    10. Li, Z.#, Liang, Y.#, Yuan, Y., Wang, L., Meng, X., Xiong, G., Zhou, J., Cai, Y., Han, N., Hua, L., Liu, G., Li, J.*, and Wang, Y*. OsBRXL4 regulates shoot gravitropism and rice tiller angle through affecting LAZY1 nuclear localization. Mol. Plant, 2019, 12: 1143-1156.

    11. Yao, R.#,Wang, L.#, Li, Y.#, Chen, L.#, Li, S., Du, X., Wang, B., Yan, J., Li, J.*, and Xie, D*. Rice DWARF14 acts as an unconventional hormone receptor for strigolactone.J. Exp. Bot., 2018, 69: 2355-2365.

    12. Hu, Q.#, He, Y.#, Liu, S., Meng, X.,Wang, L., Liu, G., Jing, Y., Chen, M., Song, X., Jiang, L., Yu, H., Wang, B.*, and Li, J*. DWARF14, a receptor covalently linked with the active form of strigolactones, undergoes strigolactone-dependent degradation in rice.Front. Plant Sci., 2017, 8:1935.

    13. Yao, R.#, Ming, Z.#, Yan, L.#, Li, S.#, Wang, F., Ma, S., Yu, C., Yang, M., Chen, L., Li, Y., Yan, C., Miao, D., Sun, Z., Yan, J., Sun, Y.,Wang, L., Chu, J., Fan, S., He, W., Deng, H., Nan, F., Li, J., Rao, Z.*, Lou, Z.*, Xie D*. DWARF14 is a non-canonical hormone receptor for strigolactone.Nature, 2016, 536: 469-473.

    14. Wang, L.#, Wang, B.#, Jiang, L., Liu, X., Li, X., Lu, Z., Meng, X., Wang, Y., Smith, S.M., and Li, J*. Strigolactone signaling in Arabidopsis regulates shoot development by targeting D53-Like SMXL repressor proteins for ubiquitination and degradation.Plant Cell, 2015, 27: 3128-3142.

    15. Wang, L.#, Guo, Y.#, Jia,L., Chu, H., Zhou, S., Chen, K., Wu, D., and Zhao, L*.Hydrogen peroxide acts upstream of nitric oxide in the heat shock pathway in Arabidopsis seedlings. Plant Physiol., 2014, 164: 2184-2196.

    16. Jiang, L.#, Liu, X.#, Xiong, G.#, Liu, H.#, Chen, F.,Wang, L., Meng, X., Liu, G., Yu, H., Yuan, Y., Yi, W., Zhao, L., Ma, H., He, Y., Wu, Z., Melcher, K., Qian, Q., Xu, H.*, Wang,.Y.*, Li, J*. DWARF 53 acts as a repressor of strigolactone signalling in rice.Nature, 2013, 504:401-405.

    17. Xuan, Y.#, Zhou, S.#,Wang, L., Cheng, Y., and Zhao, L*. Nitric oxide functions as a signal and acts upstream of AtCaM3 in thermotolerance in Arabidopsis seedlings. Plant Physiol., 2010, 153: 1895-1906.

    获奖及荣誉: