Transcriptional regulation of the immune receptor FLS2 controls the ontogeny of plant innate immunity----中国科学院遗传发育所农业资源研究中心

论文题目	Transcriptional regulation of the immune receptor FLS2 controls the ontogeny of plant innate immunity
作　　者	Yanmin Zou（邹艳敏），Shuangfeng Wang（王双凤）, Yuanyuan Zhou（周圆圆）, Jiaojiao Bai（白姣姣），Guozhong Huang（黄国中）, Xiaotong Liu（刘晓彤）, Yingying Zhang（张莹莹）, Dingzhong Tang（唐定中）, Dongping Lu（吕东平）;
发表年度	2018
刊物名称	Plant Cell
卷、期、页码	Published Online; ;
影响因子
论文摘要	Innate immunity plays a vital role in protecting plants and animals from pathogen infections. Immunity varies with age in both animals and plants. However, little is known about the ontogeny of plant innate immunity during seedling development. We report here that Arabidopsis miR172b regulates the transcription of the immune receptor FLAGELLIN-SENSING 2 (FLS2) through TARGET OF EAT1 (TOE1) and TOE2, which directly bind to the FLS2 promoter and inhibit its activity. The level of miR172b is very low in the early stage of seedling development, but increases over time, which results in decreased TOE1/2 protein accumulation and, consequently, increased FLS2 transcription and the ontogeny of FLS2-mediated immunity during seedling development. Our study reveals a role for the miR172b-TOE1/2 module in regulating plant innate immunity, and elucidates a regulatory mechanism underlying the ontogeny of plant innate immunity.
全文链接	https://doi.org/10.1105/tpc.18.00297
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